青年学者

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  • 金雪敏副教授
  • 性别:男
  • 职称:副教授
  • 硕导/博导:博导
  • 学科专业:人兽共患寄生虫免疫,寄生虫与病毒共感染免疫
  • 最高学位:博士
  • 研究方向:人兽共患病学
  • 最高学历:研究生
  • 邮箱:jinxm666@163.com

讲授课程

硕士生:重大疫病风险评估及应急处理

教育经历

(1)2017/09-2020/12:suncitygroup太阳集团,兽医公共卫生学,博士学位

(2)2015/09-2017/06:suncitygroup太阳集团,临床兽医学,硕士学位

(3)2010/09-2015/06:suncitygroup太阳集团,动物医学,学士学位

工作经历

(1)2022/12-至今:suncitygroup太阳集团,副教授/唐敖庆青年学者

(2)2010/09-2015/06:suncitygroup太阳集团,博士后/鼎新学者

科研项目

(1)国家自然科学基金委员会,青年科学基金项目,基于NLRP6活化抗旋毛虫感染的机制研究,2023-01-01至2025-12-31,30万,主持;

(2)中国博士后科学基金会,中国博士后科学基金特别资助(站中),旋毛虫早期II型免疫快速启动蛋白的分离鉴定及免疫保护作用研究,2022-01至2022-12,18万,主持;

(3)中国博士后科学基金会,中国博士后科学基金面上项目,基于NLRP3活化抗旋毛虫感染的机制研究,2022-01至2022-12,8万,主持;

(4)suncitygroup太阳集团人才引进科研启动基金,30万,主持;

(5)科技部,重点研发项目,动物重要寄生虫病新型疫苗创制,2023-12至2026-12,100万,子课题负责人;

(6)科技部,重点研发项目,MEmE食品链包虫病多个中心检测方法研发,2022-09至2025-08,90万,子课题负责人;

(7)国家自然科学基金委员会,重点项目,旋毛虫II型免疫反应快速启动分子的分离、鉴定及其分子机制研究,2023-01-01至2027-12-31,269万,主要参与人。

学术论文

以第一作者或通讯作者(含共同)在Gut MicrobesPlos PathogensmBioSTTT等领域内知名期刊发表SCI论文24篇,其中15篇中科院1区。

(1)Wang J#, Zhao X#, Li X*,Jin X*Akkermansia muciniphila: a deworming partner independent of type 2 immunity.Gut Microbes2024 16:2338947.中科院1区,IF=12.2

(2)Wang J#, Liu X#, Sun R., Mao H., Liu M*,Jin X*Akkermansia muciniphila participates in the host protection against helminth-induced cardiac fibrosis via TLR2.PLoS Pathogens2023 19:e1011683.中科院1区,IF=5.5

(3)Cao Z#, Wang J#, Liu X., Liu Y., Li F., Liu M., Chiu S*,Jin X*Helminth alleviates COVID-19-related cytokine storm in an IL-9-dependent way.mBio2024:e0090524.中科院1区,IF=5.1

(4)Jin X#, Liu Y#, Wang J#, Wang X., Tang B., Liu M*, Liu X*β-Glucan-triggered Akkermansia muciniphila expansion facilitates the expulsion of intestinal helminth via TLR2 in mice.Carbohydr Polym2022 275:118719.中科院1区,IF=11.2

(5)Liu X.#, Liu Y.#,Jin X.#, He Z.#, Huang Z.#, Sun S., Gao Y., Li J., Ning Q., Xie Z.*, Jin N.*, Liu M.* Rapidly developable therapeutic-grade equine immunoglobulin against the SARS-CoV-2 infection in rhesus macaques.Signal Transduct Target Ther2022 7:219.中科院1区,IF=39.3

(6)Wang J.#, Chen J.#, Li L., Zhang H., Pang D., Ouyang H.,Jin X.*, Tang X.* Clostridium butyricum and Bifidobacterium pseudolongum Attenuate the Development of Cardiac Fibrosis in Mice.Microbiol Spectr2022 10:e0252422.中科院1区,IF=9.0

(7)Chen H#, Cao Z#, Liu M., Diamond M. S.,Jin X*The impact of helminth-induced immunity on infection with bacteria or viruses.Vet Res2023 54:87.中科院1区,IF=3.7

(8)Jin X#., Bai X#., Yang Y#., Ding J., Shi H., Fu B., Boireau P., Liu M*., Liu X*. NLRP3 played a role in Trichinella spiralis-triggered Th2 and regulatory T cells response.Vet Res2020 51:107.中科院1区,IF=3.7

(9)Mao H#, Liu Y#, Lv Q, Li C, Yang Y, Wu F, Xu N*,Jin X*.The effect ofβ-Glucan induced intestinal trained immunity against Trichinella spiralis infection. Vet Parasitol. 2024 Jun 20:110238.中科院1区,IF=2.6

(10)Sun R#, Ding J#, Yang Y., Wu F., Wang X., Liu M., Liu X.,Jin X*., Liu Y*. Trichinella spiralis alleviates LPS-induced acute lung injury by modulating the protective Th2 immune response.Vet Parasitol2024:110206.中科院1区,IF=2.6

(11)Wang J.#,Jin X.#, Li C., Chen X., Li Y., Liu M., Liu X.*, Ding J.* In vitro knockdown of TsDNase II-7 suppresses Trichinella spiralis invasion into the host's intestinal epithelial cells.PLoS Negl Trop Dis2023 17:e0011323.中科院1区,IF=3.4

(12)Wang J#,Jin X#, Yan S., Zhao H., Pang D., Ouyang H., Tang X*, Yeastβ-glucan promotes antiviral type I interferon response via dectin-1,Veterinary Microbiology. 2024:110107.中科院1区,IF=3.3

(13)Jin X#., Liu X#., Ding J#., Zhang L., Yang Y., Wang X., Yang Y*., Liu M*. Lentinan improved the efficacy of vaccine against Trichinella spiralis in an NLRP3 dependent manner.PLoS Negl Trop Dis2020 14:e0008632.中科院1区,IF=4.4

(14)Jin X#., Yang Y#., Ding J., Liu X., Shi H., Luo X., Jia W., Cai X., Vallee I., Boireau P., Bai X*., Liu M*. Nod-like receptor pyrin domain containing 3 plays a key role in the development of Th2 cell-mediated host defenses against Trichinella spiralisinfection.Vet Parasitol2021 297:109159.中科院1区,IF=2.8

(15)Jin X#., Zhang W#., Ding Z., Wang H., Wu D., Xie X., Lin T., Fu Y., Zhang N., Cao Y. Efficacy of the Rabbit Polyclonal Anti-leptospira Antibody against Homotype or Heterotype Leptospira Infection in Hamster.PLoS Negl Trop Dis2016 10:e0005191.中科院1区,IF=3.8

(16)Jin X.#, Liu Y.#, Vallee I., Karadjian G., Liu M.*, Liu X.* Lentinan -triggered butyrate-producing bacteria drive the expulsion of the intestinal helminth Trichinella spiralis in mice.Front Immunol2022 13:926765.中科院2区,IF=7.3

(17)Jin X#., Bai X#., Zhao Y., Dong Z., Pang J., Liu M., Liu X. Nrf2 Participates in M2 Polarization by Trichinella spiralis to Alleviate TNBS-Induced Colitis in Mice.Front Immunol2021 12:698494.中科院2区,IF=8.8

(18)Liu Y., Liu X., Yang L., Qiu Y., Pang J., Hu X., Dong Z., Liu Z.,Jin X*. Adjuvanticity ofβ-Glucan for Vaccine Against Trichinella spiralis.Front Cell Dev Biol2021 9:701708.中科院2区,IF=5.5

(19)Pang J.#,Jin X.#, Liu Y.#, Dong Z.#, Ding J., Boireau P., Vallee I., Liu M, Xu N.*, Liu X.* Trichinella spiralis inhibits myoblast differentiation by targeting SQSTM1/p62 with a secreted E3 ubiquitin ligase.iScience2024 27:109102.

(20)Wang J.#, Tang B.#, You X., Cai X., Jia W., Liu X., Liu M.,Jin X.*, Ding J.* Trichinella spiralis excretory/secretory products from adult worms inhibit NETosis and regulate the production of cytokines from neutrophils.Parasit Vectors2023 16:374.

(21)Liu Y., Dong Z., Pang J., Liu M*.,Jin X*. Prevalence of meat-transmitted Taenia and Trichinella parasites in the Far East countries.Parasitol Res2021 120:4145-4151.

(22)Qu Z#.,Jin X#., Wang Y., Yang Y., Yang Li, Bai X., Yang Y., Xu N., Wang X., Liu M. Effect of recombinant serine protease from newborn larval stage of Trichinella spiralis on 2,4,6-trinitrobenzene sulfonic acid-induced experimental colitis in mice.Acta Trop2020 211:105553.

(23)Jin X., Yang Y., Liu X., Shi H., Cai X., Luo X., Liu M., Bai X. Glutathione-S-transferase of Trichinella spiralis regulates maturation and function of dendritic cells.PARASITOLOGY2019 146:1725-1732.

(24)Jin X., Yang Y., Bai X., Shi H., Zhang W., Zhang Z., Jia W., Lin J., Liu M., Liu X. Dendritic cells treated by Trichinella spiralis muscle larval excretory/secretory products alleviate TNBS-induced colitis in mice.Int Immunopharmacol2019 70:378-386.


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