本科生：动物寄生虫病学、人兽共患病学

硕士生：预防兽医学实践

1. 2008年9月~2013年6月suncitygroup太阳集团动物医学专业，获农学学士学位

2. 2013年9月~2018年6月suncitygroup太阳集团预防兽医学专业，获农学博士学位

1. 2018年11月~2021年9月suncitygroup太阳集团，讲师、团队预留博士后

2. 2021年10月~至今suncitygroup太阳集团，副教授

1.寄生虫（隐孢子虫与贾第虫）的检测、分离与评估—PARADISE，国家重点研发计划“政府间国际科技创新合作”，项目编号：2022YFE0114500，2022.07-2025.06，90万，课题负责人。

2.贾第虫巨噬细胞迁移抑制因子在贾第虫致病中的作用机制研究，国家自然基金青年科学基金项目，项目编号：32202834，2023.01-2025.12，30万，主持。

3.新孢子虫弱毒株制备及保护效果评价，吉林省科技发展计划项目-重点研发，项目编号：20240303078NC，2024.01-2026.12，50万，主持。

4.NLRs在宿主抗贾第虫感染中的分子识别机制，吉林省科技发展计划创新平台（基地）和人才专项，项目编号：20220508047RC，2022.01-2023.12，15万，主持。

5.托曲珠利混悬液比对试验，横向项目，项目编号：20210065，2021.03-2023.03，135万，主持。

6.suncitygroup太阳集团“励新优秀青年教师培养计划”，重点培养阶段，2022.01-2024.12，18万，主持。

7.贾第虫病毒调控贾第虫糖酵解的作用及分子机制研究，中国博士后基金委，项目编号：2019M651213，2019.06-2021.09，8万，主持。

1.Zhang X#, Wang Y#, Gong P, Wang X, Zhang N, Chen M, Wei R, Zhang X,Li X*, Li J*. Neospora caninum Evades Immunity via Inducing Host Cell Mitophagy to Inhibit Production of Proinflammatory Cytokines in a ROS-Dependent Manner. Front Immunol. 2022 Mar 9;13:827004. doi: 10.3389/fimmu.2022.827004.

2.Wang Y#, Wang X#, Gong P, Yu Y, Zhang N, Ren Y, Ma Y, Zhao Z, Zhang X,Li X*, Li J*. Prevalence of fish-borne zoonotic trematode infection in Jilin Province, China. Int J Parasitol Parasites Wildl. 2022 Apr 16;18:52-60. doi: 10.1016/j.ijppaw.2022.04.004.

3.Li X#, Zhang X#, Gong P, Xia F, Li L, Yang Z, Li J*. TLR2-/- Mice Display Decreased Severity of Giardiasis via Enhanced Proinflammatory Cytokines Production Dependent on AKT Signal Pathway. Front Immunol. 2017 Sep 20;8:1186. doi: 10.3389/fimmu.2017.01186.

4.Li X, Wang X, Gong P, Zhang N, Zhang X, Li J*. Analysis of Codon Usage Patterns in Giardia duodenalis Based on Transcriptome Data from GiardiaDB. Genes (Basel). 2021 Jul 29;12(8):1169. doi: 10.3390/genes12081169.

5.Zhang X#,Li X#, Yu Y, Zhang X, Wang X, Zhang N, Chen M, Gong P*, Li J*. Giardia lamblia regulates the production of proinflammatory cytokines through activating the NOD2-Rip2-ROS signaling pathway in mouse macrophages. Immunol Cell Biol. 2022 Apr 2. doi: 10.1111/imcb.12550.

6.Wei R#,Li X#, Wang X, Wang Y, Zhang X, Zhang N, Wang J, Yang J, Zhang X, Gong P*, Li J*. Trypanosoma evansi triggered neutrophil extracellular traps formation dependent on myeloperoxidase, neutrophil elastase, and extracellular signal-regulated kinase 1/2 signaling pathways. Vet Parasitol. 2021 Aug;296:109502. doi: 10.1016/j.vetpar.2021.109502.

7.Pu X#,Li X#, Cao L#, Yue K, Zhao P, Wang X, Li J, Zhang X, Zhang N, Zhao Z, Liang M, Gong P*. Giardia duodenalis Induces Proinflammatory Cytokine Production in Mouse Macrophages via TLR9-Mediated p38 and ERK Signaling Pathways. Front Cell Dev Biol. 2021 Jul 15;9:694675. doi: 10.3389/fcell.2021.694675.

8.Zhang X#,Li X#, Gong P, Wang X, Zhang N, Chen M, Zhang X*, Li J*. Host defense against Neospora caninum infection via IL-12p40 production through TLR2/TLR3-AKT-ERK signaling pathway in C57BL/6 mice. Mol Immunol. 2021 Nov;139:140-152. doi: 10.1016/j.molimm.2021.08.019.

9.Wei R#,Li X#, Wang X, Zhang N, Wang Y, Zhang X, Gong P*, Li J*. Trypanosoma evansi evades host innate immunity by releasing extracellular vesicles to activate TLR2-AKT signaling pathway. Virulence. 2021 Dec;12(1):2017-2036. doi: 10.1080/21505594.2021.1959495.

10.Gao Y#,Li X#, Zhang N#, Zhao P, Li S, Tai L, Li X, Li L, Li J, Zhang X, Sun M, Cao L*, Gong P*. Trichomonas vaginalis induces extracellular trap release in mouse neutrophils in vitro. Acta Biochim Biophys Sin (Shanghai). 2021 Dec 8;53(12):1736-1738. doi: 10.1093/abbs/gmab139.

11.Wang X#,Li X#, Gong P#, Zhang N, Li L, Ouyang H, Jia L, Li J*, Zhang X*. Pyroptosis executioner gasdermin D contributes to host defense and promotes Th 1 immune response during Neospora caninum infection. Vet Parasitol. 2020 Oct;286:109254. doi: 10.1016/j.vetpar.2020.109254. Epub 2020 Sep 22. PMID: 33032075.

12.Li L#,Li X#, Li G#, Gong P, Zhang X, Yang Z, Yang J, Li J*. Mouse macrophages capture and kill Giardia lamblia by means of releasing extracellular trap. Dev Comp Immunol. 2018 Nov;88:206-212. doi: 10.1016/j.dci.2018.07.024. Epub 2018 Jul 24. PMID: 30048699.

13.Li L#,Li X#, Gong P, Zhang X, Yang Z, Yang J, Li J*. Trichomonas vaginalis Induces Production of Proinflammatory Cytokines in Mouse Macrophages Through Activation of MAPK and NF-κB Pathways Partially Mediated by TLR2. Front Microbiol. 2018 Apr 10;9:712. doi: 10.3389/fmicb.2018.00712. PMID: 29692771; PMCID: PMC5902545.

[1]丁聪,翟涛,李玲,王晓岑,宫鹏涛,张西臣,李建华,李新*.1株鸽毛滴虫的分离鉴定、体外培养和感染动物模型的建立[J/OL].中国兽医学报,2022(05):2-7+1[2022-06-09].DOI:10.16303/j.cnki.1005-4545.2022.05.14.

入选suncitygroup太阳集团“励新优秀青年教师培养计划”

1.吉林省寄生虫学会理事

2.Frontiers in Cellular and Infection Microbiology杂志审稿人