基础兽医学系

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  • 隋婷婷副教授
  • 性别:女
  • 职称:副教授
  • 硕导/博导:博导
  • 学科专业:基础兽医学
  • 最高学位:博士
  • 研究方向:基因编辑技术挖掘及优化;人源化动物模型的构建及应用
  • 最高学历:研究生
  • 邮箱:suitingting@jlu.edu.cn

讲授课程

本科生:动物学

教育经历

2016.09-2019.06,suncitygroup太阳集团,基础兽医学,博士学位

2014.09-2016.06,suncitygroup太阳集团,基础兽医学,硕士学位

2010.09-2014.06,西南大学,动物医学,学士学位

工作经历

2022.09-至今,suncitygroup太阳集团,suncitygroup太阳集团,副教授

2019.07-2022.09,suncitygroup太阳集团,suncitygroup太阳集团,讲师

2019.07-2021.07,suncitygroup太阳集团,suncitygroup太阳集团,博士后

科研项目

1.国家自然科学基金青年项目,32101226,人源化CD300LF抗兔瘟病毒基因修饰兔的构建,2022-01至2024-12,30万元,主持;

2.中国科协资助青年人才托举工程项目,YESS20210189,2021-01至2023-12,45万元,主持;

3.吉林省教育厅科学研究项目,JJKH20211055KJ,人源化ACE2基因修饰兔模型的构建,2021-01至2022-12,2.5万元,结题,主持;

4.中国博士后科学基金面上资助二等,2020M670859,Duchenne型肌营养不良症模型兔的构建及治疗策略研究,2020-07至2021-07,8万元,结题,主持;

5.中国博士后特别资助(站前),2019TQ0113,人源化胰腺嵌合体兔模型的构建,2019-07至2021-07,18万元,结题,主持。

学术论文

1.Tao Zhang#;Feiyu Zhao#; Jinze Li#; Xiaodi Sun; Xiyun Zhang; Hejun Wang; Peng Fan;Liangxue Lai*; Zhanjun Li* andTingting Sui*, Programmable RNA 5-methylcytosine (m5C) modification of cellular RNAs by dCasRx conjugated methyltransferase and demethylase,Nucleic Acids Research, 2024, 1-16.(IF:14.9,中科院一区TOP)

2. Feiyu Zhao#; Tao Zhang#; Xiaodi Sun; Xiyun Zhang; Letong Chen; Hejun Wang; Jinze Li; Peng Fan; Liangxue Lai*;Tingting Sui*; Zhanjun Li*; A strategy for Cas13 miniaturization based on the structure and AlphaFold, Nature Communications, 2023, 14(1), 5545. (IF:16.6,中科院一区TOP)

3.Jinze Li#, Ding Zhao#, Tao Zhang#, Haoyang Xiong, Mingyang Hu, Hongmei Liu, Feiyu Zhao, Xiaodi Sun, Peng Fan, Yuqiang Qian, Di Wang, Liangxue Lai*,Tingting Sui*, Zhanjun Li*,Precise large-fragment deletions in mammalian cells and mice generated by dCas9-controlled CRISPR/Cas3, ScienceAdvances, 2024, 2.(IF:13.6,中科院一区TOP)

4.Tingting Sui#; Yuning Song#; Zhiquan Liu;Mao Chen; Jichao Deng;Yuanyuan Xu; Liangxue Lai*; Zhanjun Li*; CRISPR-induced exon skipping is dependent on premature termination codon mutations, Genome Biology, 2018, 19(1).(IF:14.028,中科院一区TOP)

5.Mao Chen#;Tingting Sui#; Li Yang#; Yuqiang Qian; Zhiquan Liu; Yongsai Liu; Gerong Wang; LiangxueLai*; ZhanjunLi*; Live imaging of RNA and RNA splicing in mammalian cells via the dcas13a-SunTag-BiFC system, Biosensors and Bioelectronics, Volume 204, 15May 2022, 114074. (IF:12.55,中科院一区TOP)

6.Peng Fan#; Hejun Wang#;·Feiyu Zhao; Tao Zhang; Jinze Li; Xiaodi Sun; Yongduo Yu;·Haoyang Xiong;Liangxue Lai*;Tingting Sui*, Targeted mutagenesis in mice via an engineered AsCas12f1 system, Cellular and Molecular Life Sciences, 2024, 81:63.(IF:8)

7. Yuqiang Qian#; Ding Zhao#;Tingting Sui#; Mao Chen; Zhiquan Liu; Hongmei Liu; Tao Zhang; Siyu Chen; Liangxue Lai*; Zhanjun Li*; Efficient and precise generation of Tay-Sachs disease model in rabbitby prime editing system, Cell discovery, 2021, 7(1):50.(IF:38.08,中科院一区TOP)

8.Tingting Sui#; Di Liu#; Tingjun Liu; Jichao Deng; Mao Chen; Yuanyuan Xu; Yuning Song; Hongsheng Ouyang; Liangxue Lai*; Zhanjun Li*; LMNA-mutated Rabbits: A Model of Premature Aging Syndrome with Muscular Dystrophy and Dilated Cardiomyopathy, Aging and Disease, 2019, 10(1): 102-115. (IF:9.96,中科院一区TOP)

9.Mingyang Hu#; Xiyun Zhang#; Jinze Li#; Luotong Chen; Xiaolin He;Tingting Sui*; Fucosyltransferase 2: A Genetic Risk Factor for Intestinal Diseases, Frontiers in Microbiology, Volume13, July 2022, 940196. (IF:6.064)

10.Tao Zhang#; JinZe Li#;Tian Wang; Feiyu Zhao;Tingting Sui*; No apparent p53 activation in CRISPR-engineered gene-edited rabbits, Journal of Cellular and Molecular Medicine, 2021, 25(21):10313-10317. (IF:5.31)

11.Tao Zhang#;Hongwu Yao#; Hejun Wang;Tingting Sui*; Development of Woolly Hair and Hairlessness in a CRISPR−Engineered Mutant Mouse Model with KRT71 Mutations, Cells, 2023, 12(13), 1781. (IF:6)

12.Tingting Sui; Li Xu; Yeh Siang Lau; Di Liu; Tingjun Liu; Yandi Gao; Liangxue Lai*; Renzhi Han*; Zhanjun Li*; Development of muscular dystrophy in a CRISPR-engineered mutant rabbit model with frame-disrupting ANO5 mutations, Cell Death & Disease, 2018,9(6). (IF:5.98,中科院一区TOP)

13.Tingting Sui; Yeh Siang Lau; Di Liu; Tingjun Liu; Li Xu; Yandi Gao; Liangxue Lai*; Zhanjun Li*; Renzhi Han*; A novel rabbit model of Duchenne muscular dystrophy generated by CRISPR/Cas9, Disease Models & Mechanisms, 2018,11(6). (IF:4.69)

14.Tingting Sui; Yeh Siang Lau; Di Liu; Tingjun Liu; Li Xu; Yandi Gao; Liangxue Lai*; Zhanjun Li*; Renzhi Han*; A novel rabbit model of Duchenne muscular dystrophy generated by CRISPR/Cas9, DiseaseModels & Mechanisms, 2018,11(6). (IF:4.69)

15.Mingming Liang#;Tingting Sui#; Zhiquan Liu; Mao Chen; Hongmei Liu; Huanhuan Shan; Liangxue Lai*; Zhanjun Li*; AcrIIA5 Suppresses Base Editors and Reduces Their Off-Target Effects, Cells, 2020, 27;9(8):1786. (IF:6.6)

16.Tingting Sui; Hongwu Yao; Tao Zhang; Jinze Li; Liangxue Lai*; Zhanjun Li*; The Genetic Mutation of ANO5 in Rabbits Recapitulates Human Cardiomyopathy, Applied sciences, 2020, 10: 4976. (IF:2.679)

17.隋婷婷;赖良学;袁琳;李占军;刘欢;采用敲除技术建立低磷性佝偻病模型的方法, 2019-5-7,专利号:ZL201510557129.7.

18.李占军;隋婷婷;李金泽;张涛;赵飞宇;范鹏;孙小迪;基于CRISPR技术制备高产抗体兔的方法,2023-10-24,专利号:ZL 2022 1 0683437.4.

获奖情况

1. 2022年入选第七届中国科协青年人才托举工程

2.2022年获得吉林省优秀博士论文

3.隋婷婷,人源化ACE2基因修饰兔模型的构建,吉林省教育厅,优秀结项项目,2022

社会兼职

1. Genes杂志客座编辑

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